Neuromotor Pen Parkinsons Diagnostics

Changing the way we diagnose
and monitor neuromotor impairments

Make a difference today

Faster, simpler, differential diagnosis

There is a clear need for improved technology solutions in diagnosis

Neuromotor Pen

Non-Invasive

The NeuroMotor Pen is a unique, non-invasive, patented medical device that supports an earlier and more accurate diagnosis and offers monitoring of neuromotor impairments.

Neuromotor Pen Sensor Technologies

Sensor Technologies

The NeuroMotor Pen, with built-in highly accurate sensor technologies, combined with its analytical software, processes minute limb and hand motion parameters to quantify fine motor skills, represented by ‘motion features’.

Neuromotor Pen Clinical Information

Additional Clinical Information

These motion features are clinically validated biomarkers and provide objective information to clinicians about movement abnormalities, to support differential diagnosis and clinical management of Parkinson's disease and other neuromotor impairments.

Neuromotor Pen Streamlining Neuromotor Services

Streamlining Neuromotor Services

The NeuroMotor Pen is an innovative technology for use in triage to support general practitioners to make a more accurate assessment before referral to neuromotor specialists services to increase the efficiency of specialist services and reduce costs.

Investors

Partner logo Par Equity
northstar
sis
craiglburr
occ
sib

How the
NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

The NeuroMotor Pen™ offers an accurate and objective
assessment for differential diagnosis and clinical management
of patients with neuromotor impairments, as well as
supporting drug management which can change a patient's
neuromotor functions.

The NeuroMotor Pen™ offers an accurate and objective
assessment for differential diagnosis and clinical management
of patients with neuromotor impairments, as well as
supporting drug management which can change a patient's
neuromotor functions.

The NeuroMotor Pen™ offers an accurate and objective
assessment for differential diagnosis and clinical management
of patients with neuromotor impairments, as well as
supporting drug management which can change a patient's
neuromotor functions.

How the
NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

Patients complete a set of standardized NeuroMotor™ Pen handwriting and drawing tasks
with the NeuroMotor™ Pen App on a high-end tablet PC. The tasks were developed to derive as much information about the subject’s neuromotor processing with relatively few tasks.

The Pen has a wireless connection with the tablet, from where the data is sent to the cloud application, where the NeuroMotor™ Pen algorithms analyse the minute limb
and hand motion to provide the results in the App.

SmartPoints™ cybersecurity to medical standards is applied on the tablet, as well as for the data in transit and on the cloud.

Patients complete a set of standardized NeuroMotor™ Pen handwriting and drawing tasks
with the NeuroMotor™ Pen App on a high-end tablet PC.
The tasks were developed to derive as much information about the subject’s
neuromotor processing with relatively few tasks.

The Pen has a wireless connection with the tablet, from where the data is sent to the
cloud application, where the NeuroMotor™ Pen algorithms analyse the minute limb
and hand motion to provide the results in the App.

SmartPoints™ cybersecurity to medical standards is applied on the tablet,
as well as for the data in transit and on the cloud.

Patients complete a set of standardized NeuroMotor™ Pen handwriting and drawing tasks
with the NeuroMotor™ Pen App on a high-end tablet PC. The tasks were developed to derive as much information
about the subject’s neuromotor processing with relatively few tasks.

The Pen has a wireless connection with the tablet, from where the data is sent to the
cloud application, where the NeuroMotor™ Pen algorithms analyse the minute limb
and hand motion to provide the results in the App.

SmartPoints™ cybersecurity to medical standards is applied on the tablet,
as well as for the data in transit and on the cloud.

How the
NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

The results of the NeuroMotor Pen™ motor skill tests are presented
as biomarkers with an easy to interpret numerical format
on the graphical user interface.

The results of the NeuroMotor Pen™ motor skill tests are presented
as biomarkers with an easy to interpret numerical format
on the graphical user interface.

The results of the NeuroMotor Pen™ motor skill tests are presented
as biomarkers with an easy to interpret numerical format
on the graphical user interface.

How the
NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

The NeuroMotor™ Pen with analytical software that calculate the biomarkers can non-invasively differentiate between Parkinson’s and other disease or signs normal ageing that may mimic
the symptoms of Parkinson’s disease.

In addition to scoring biomarkers, a second level of outcome presentation
allows to categorise the results in, for example, likelihood of Parkinson’s vs Essential Tremor or other disease classification.

The NeuroMotor™ Pen with analytical software that calculate the biomarkers can non-invasively
differentiate between Parkinson’s and other disease or signs normal ageing that may mimic
the symptoms of Parkinson’s disease.

In addition to scoring biomarkers, a second level of outcome presentation
allows to categorise the results in, for example, likelihood of Parkinson’s vs Essential Tremor
or other disease classification.

The NeuroMotor™ Pen with analytical software that calculates the biomarkers can non-invasively
differentiate between Parkinson’s and other disease or signs normal ageing that may mimic
the symptoms of Parkinson’s disease.

In addition to scoring biomarkers, a second level of outcome presentation
allows to categorise the results in, for example, likelihood of Parkinson’s vs Essential Tremor
or other disease classification.

How the
NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

How the NeuroMotor Pen™ works

Manus Neurodynamica provides a robust and secure
data-processing and analysis architecture including
a cloud-based facility to allow clinicians to store
the test data safely and anonymously.

Manus Neurodynamica provides a robust and secure
data-processing and analysis architecture including
a cloud-based facility to allow clinicians to store
the test data safely and anonymously.

Manus Neurodynamica provides a robust and secure
data-processing and analysis architecture including
a cloud-based facility to allow clinicians to store
the test data safely and anonymously.

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NeuroMotor Pen

Accurately Assessing Fine Motor Skills

There are many symptoms of Parkinson’s disease. However, minor changes of fine motor control of the fingers, leading to bradykinesia – slowness of motion – micrographia – small handwriting – as well as tremors are often early indicators of Parkinson's disease.

Initially, these symptoms can be very subtle and hardly noticeable. Our clinical trials and over 10 years of research have demonstrated that the NeuroMotor Pen is capable of detecting these early signs with high accuracy.

Using information gathered from a set of standardised handwriting and drawing tasks, the NeuroMotor Pen provides an accurate and objective patient assessment to clinicians, offering an earlier, non-invasive diagnostic of Parkinson’s disease.

People with Parkinson's disease have a hard time controlling movement due to the neurodegeneration in parts of the brain, which can make fine motor skills like writing more difficult. Early detection and treatment improve general patient outcomes and the chance of maintaining good motor function.

Make a Difference Today

Manus Neurodynamica is revolutionising neuromotor health care management by using their patented technology and unique diagnostic algorithms to record validated biomarkers of neuromotor impairments and differentiate between movements, to radically improve patient diagnosis and disease management.

As side effects of antipsychotic medications lead to Parkinsonism – symptoms that mimic the movement abnormalities in Parkinson’s, Manus Neurodynamica has been investigating the use of the NeuroMotor Pen in the application of optimising anti-psychotic drug intake. A pilot study has already shown very encouraging results.

The handwriting and symptoms in patients before and after taking anti-psychotic medication is being rated with the NeuroMotor Pen biomarkers to see if identifiable changes can help provide information about optimal dosage and assist with the monitoring of side effects.

Collaborators

Partner logo Northumbria Healthcare
fraunhofer
npc
nihr
Partner logo VTT
inotec
edinburgh
Partner logo UMCG
glassgow
eu commisson
Partner logo SBRI
Partner logo cambridge cognition
Partner logo Stabilo
parkinsonsuk
pattern
Manus Icon white accuracy

The NeuroMotor Pen can help improve the accuracy of early differential diagnosis by specialists in case of diagnostic uncertainty and help general practitioners to improve their referral accuracy and reduce unnecessary referrals to Parkinson's specialists.

Manus Icon cost reduction

Using the NeuroMotor Pen can offer a direct cost reduction for disease diagnosis as replacement for more expensive methods and assist with a timely, accurate diagnosis, that increases early treatment and avoids patient deterioration to the stage where intervention long-term care costs increase. The latter typically represents 70% of costs for Parkinson’s care.

Manus Icon reduced wait time

Waiting list times for diagnosis and treatment can be reduced using the NeuroMotor Pen as less experienced clinicians and non-specialist healthcare workers can carry out initial tests to triage patients with suspected neuromotor impairments.

Make a difference today

Our disruptive technology has the potential to be used across many applications such as screening and triage, diagnosis, drug treatment optimisation, drug development, rehabilitation and research to improve our understanding of neuromotor impairments. We are keen to continue collaborating with interested researchers, clinicians and practitioners on our research in different areas, as well as businesses for further development and rolling out the existing and new products worldwide.